Discontinuation of Methotrexate in Psoriasis

Discontinuation of methotrexate in psoriasis.

Erythrodermic psoriasis after discontinuation of ixekizumab

INTRODUCTION Erythroderma is defined as generalized redness and scaling affecting more than 90% of the skin surface and often accompanied by systemic complications such as hypothermia, dehydration, and electrolyte imbalance. Treatment is targeted at the underlying cause, and preexisting dermatoses are identified in 65% of patients. Psoriasis is the most common underlying disease in erythrodermi...

Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference.

BACKGROUND Methotrexate remains a valuable option for the treatment of psoriasis. This report will summarize studies regarding the use of methotrexate since the last guidelines were published in 1998. OBJECTIVE A task force of the National Psoriasis Foundation Medical Board was convened to evaluate treatment options. Our aim was to achieve a consensus on new updated guidelines for the use of ...

[Guidelines on the use of methotrexate in psoriasis].

Psoriasis, a chronic multifactorial inflammatory disease that develops in genetically predisposed individuals, affects approximately 1.5% of the Spanish population. This disease has a negative impact on patients' quality of life, and long-term therapy is often required to control the symptoms. In addition to the classical systemic treatments (methotrexate, acitretin, cyclosporine, and ultraviol...

Efficacy of Methotrexate in patients with plaque type psoriasis

OBJECTIVE To assess the efficacy of Methotrexate in patients with plaque type psoriasis. METHODS This descriptive study was conducted in the department of Dermatology, Civil Hospital Karachi from September 2009 to March 2010. Seventy three patients between 18 to 50 years of age suffering from plaque type psoriasis with PASI score of >10 were included in the study after taking the informed con...